There's a Painkiller: Resurrection Preview on IGN with first news of a planned next installment in the Painkiller series of first-person shooters. The game is in development at Homegrown Games, the third developer in three games for this series that originated with Polish developer People Can Fly. Here's a bit that describes some gameplay:

The Painkiller weapon is one of the stars of the series, so it's no shock that Wild Bill would get his hands on it right away. The main fire mode activates spinning blades that chew through enemies at close range. The secondary fire option sends the blades spinning out from the weapon, damaging enemies in its path. From there the weapon can either fire energy beams in the direction of the blades, or activate the secondary fire again to recall the blades and use them for melee attacks. Soon enough, the Painkiller's unique applications will be put to the test as Wild Bill is set upon by a number of monsters and demons. At first, the player is fighting purely out of an instinct to stay alive but as the game unfolds, the battles will take on a new purpose and new layers of meaning.