Volition's site has been updated with this bit of news that should be of the highest importance to Freespace 2 players (thanks Billy):

Unfortunately we have encountered a problem with the original shipment of Freespace 2 on some Windows95a or Windows95OSR2 systems. The problem causes the title to repeatedly ask for CD#2, even with the correct CD in the drive. This does not mean that your CD is damaged or needs replacement. We regret that the problem was discovered after the product had been shipped, but we were able to pinpoint and correct this problem immediately, and have already made an update available for the title, which can be installed by simply clicking the 'update' button, located on the Freespace launcher. If the title did not originally install, click on your 'Start' button, then on 'Run', and type D:\SETUP, with 'D' representing your CD-ROM drive letter. After installation, you will then be prompted with the option to update your title via the games launcher. The launcher can also be accessed (after the title has been successfully installed) by: (Start/Programs/Games/Freespace2/Freespace2).

The new version will be automatically downloaded to your system. Any future updates for the title will also be available via the update button, and we recommend that you check it periodically to assure that you are running the newest version of Freespace 2.

Note for Windows98 Users: Although we have not encountered the problem in tests with Windows98 systems, installation of the patch will in no way be detrimental to your operation of the title, and is recommended.

Again, we do apologize for any inconvenience that this may cause. We do our best to verify that our products go out as clean as possible, and hope that you understand that we are working to resolve this situation immediately. We hope that you enjoy playing Freespace 2 as much as we enjoyed creating it for you. If you need additional assistance, please feel free to contact our support department at support@interplay.com.