Large Cyberpunk 2077 Saves Apparently Corrupted

Reports on the CD PROJEKT RED Forums and Reddit have multiple accounts of problems with large saved game files in Cyberpunk 2077 (thanks Tom's Hardware). Apparently once these grow past about 6 MB it slows down the loading process significantly and when they pass 8 MB in size they end up corrupted. The developer hasn't officially acknowledged this yet, but this post from a moderator discusses ways to protect yourself from this problem:
No, but stop loading saved games.

First, back up all of your save files by copying them to a folder on your desktop or something. Then, do a verify / repair of the game.

After that, try loading. If it still doesn't work, erase the "corrupted" saves and replace them with the backups. Keep doing this as you troubleshoot. It can often be the loading process, not the saving process that borks a save.

If you were using any sort of modification to the game (like the community's AVX fix), and you disabled it, put it back in place. Any modification to the game can leave reference data that will corrupt the game's ability to read the save files unless the modifications are also running.