An article on IGN has word that, inspired by Double Fine's success, Brian Fargo's inXile Entertainment is planning a Kickstarter campaign to launch a Wasteland sequel for PCs and possibly other platforms, though this may not actually called Wasteland 2. Here's a bit:

He doesn't know if it'd be straight up called Wasteland 2, but he repeatedly emphasized that, despite having thought about it for only 48 hours, it wouldn't be a crazy genre change up. Wasteland, whatever its called, will be "100% faithful to its roots." This means a Wasteland game that "would be focusing on top-down, probably isometric, party based, skill based -- where if you'd just finished playing Wasteland and moved onto this you'd feel comfortable."