As a lifelong PC Gamer who has dabbled in consoles from time to time, I know that I can't help but think when I'm playing a game like San Andreas (or presumably GTA4 when it is released on PC) about how much better the game would have been had it been designed for PC first. No console built to date can simulate open worlds to anywhere near as well as a mid-range PC can. When I play GTA I feel like I can actually see all of the corners that had to be cut to make the games run on hardware inferior to PC's. That's not me being snobbish; that's just me stating what I hope is obvious.
Are the Grand Theft Auto games creatively brilliant and fun? Sure. Could they have been so much better had they been designed around the superior hardware of personal computers? I certainly believe so.
"We live on a placid island of ignorance in the midst of black seas of infinity, and it was not meant that we should voyage far."
"Universal compassion is the only guarantee of morality."