HL2:Ep2 - Alyx gets whiny, expects you to do everything, still doesn't put out. Valve - your dedication to realistic characters is going too far.
Ant lions always bugged me (harhar) but Ep2 was the first to annoy me by having too many "Gordon do this" "Thanks Gordon" and so on. I know the Free Man is the hero of the resistance but it would be nice to at least have the illusion that other people aren't just cannon fodder. How about next time, you go fight through an abandoned shit hole, cross a radio active waste dump, and then jump a precariously balanced bridge in a beat up piece of crap while I snipe a couple of head crabs and smoke a joint or whatever she does to pass her free time.