Gothic 1 and 2 (no surprise since I guess they use the same engine), Homeworld 2, and a couple others that aren't springing immediately to mind. I got 'em all working eventually, but it was kinda obnoxious.
Edit: And those aren't really all that old. I still haven't really tried many of the games that are older.
This comment was edited on May 31, 19:56.