Well, Mine is set to low quality at 800x600, but this game plays and looks really nice. I have a now lower end machine and haven't noticed any stuttering/pausing or otherwise problems playing...
AMD 2400+, 512 M 2100 RAM, ATI Radeon 9000 (non-pro), with a first generation nvidia mb, and a SBLive 5.1 (in a 3.1 speaker setup).