Out of the Blue

I watched the 10th anniversary edition of Reservoir Dogs yesterday, which has resulted in a peculiar side-effect. Since watching, the song Like a Virgin keeps running through my head. As disturbing as it is to find a wretched Madonna song haunting one's subconscious, this is that much worse. First, because the song itself doesn't actually play at any point in the movie, its invasion seems that much more insidious. Second, the context of the discussion of the tune in the movie just keeps conjuring up unfortunate imagery. *Shudder*.

Links of the Day: Bad Neighbour.
Stories of the Day: Boy fends off alligator attack with swift punch.
'I'm drunk, officer, but my donkey's in charge'. Thanks Dave Claycomb.
Sherpa sets record Everest time.
Science!: Statins in Aisle 7?
Dog genes tell surprising tales. Thanks zombie69.
NASA wants to add robot planes to nation's air traffic.
Image of the Day: BananaPhone. Thanks Ant.
Media of the Day: Shrek 2 - The First 5 Minutes. Thanks Ant.
Auction of the Day: CELEBRITY AIR!!!!. But where's the A-List air? Thanks Michael Lemke.
Follow-ups: Thousands may be harbouring vCJD Never once using the words "mad cow."
Urban Legends Reference Pages (Andy Kaufman). Thanks Z. Well duh.
California town for sale on eBay finally sold.
Thanks Mike Martinez
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27.
 
vCDJ abstract
May 21, 2004, 15:01
27.
vCDJ abstract May 21, 2004, 15:01
May 21, 2004, 15:01
 
Some serious statistical mumbo jumbo to get any sort of confidence from 3 positive results.

This study aims to provide an estimate of the number of individuals in the UK who may be incubating variant Creutzfeldt-Jakob disease and at risk of causing iatrogenic spread of the disease. Lymphoreticular accumulation of prion protein is a consistent feature of variant Creutzfeldt-Jakob at autopsy and has also been demonstrated in the pre-clinical phase. Immunohistochemical accumulation of prion protein in the lymphoreticular system remains the only technique that has been shown to predict neurological disease reliably in animal prion disorders. In this study, immunohistochemistry was used to demonstrate the presence of prion protein, with monoclonal antibodies KG9 and 3F4, in surgically removed tonsillectomy and appendicectomy specimens. The samples were collected from histopathology departments across the UK and anonymised prior to testing. Samples were tested from 16 703 patients (14 964 appendectomies, 1739 tonsillectomies), approximately 60% of whom were from the age group 20-29 years at operation. Twenty-five per cent of the samples were excluded from the final analyses because they contained inadequate amounts of lymphoid tissue. Three appendicectomy samples showed lymphoreticular accumulation of prion protein, giving an estimated prevalence of 3/12 674 or 237 per million (95% CI 49-692 per million). The pattern of lymphoreticular accumulation in two of these samples was dissimilar from that seen in known cases of variant Creutzfeldt-Jakob disease. Although it is uncertain whether immunohistochemical accumulation of prion protein in the lymphoreticular system is specific for variant Creutzfeldt-Jakob disease, it has not been described in any other disease, including other forms of human prion disease or a range of inflammatory and infective conditions. These findings reinforce the importance of measures taken by the UK Department of Health to reduce the risk of spread of variant Creutzfeldt-Jakob via blood products and surgical instruments, and of the urgency to proceed with large-scale screening of fresh tonsil specimens for the presence of prion protein. Copyright 2004 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.



My e. coli cures cancer!
Playing with yeast to help you live longer!
My e. coli cures cancer!
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