I know what you are saying... I played through Mario64 and I have played many other games with similar control schemes. None of them are perfect though. I fell off many a ledge in mario and sonic. Not to mention almost everyone complains about camera controls in third person games...
All I'm saying is that it is not impossible to become acclimated to using a mouse and keyboard in a third person game.
http://www.skinnypuppy.com/the greater wrong of the right --
http://www.spv.de/eng/skinnypuppy/default.html