One of the biggest works of art is you can now play the full game in Coop! It's an amazing set of fixes and is the definitive Unofficial Patch. It's pretty unbelievable if you get a chance to check out the list of changes and fixes.
Most features are a choice, like adding addiction when drinking vampire blood (which is in the rulebook, iirc). The AI is much smarter, especially the usage of disciplines and not wasting blood. Many disciplines now last much longer and things like Enchantment last until canceled. Meaning you can enthrall an enemy and it stays with you as a pet, until it dies fighting for you or until you release/kill it.
Scorpio Slasher: ... What about you boy, what do hate?
Marcus: ... Bullies. Tiny dick egotists who hurt people for no reason, make people lock their doors at night. People who make general existence worse, people like you.