i've got some simulation programs that i run from time to time (not for work, just hobby), BeyondTV (DVR) runs strangely; Sensiva, a mouse gesturing program that i use constantly; 'reget' plugin for Firefox also acts strangely in 7.
yes, most of'em are somewhat obscure and it's probably time to ditch'em at some point, but these programs are so specialized that there are no close substitutes.
i've already bought and tried W7-64bit already, but had to downgrade after finding out how many things it broke with my (heavily-customized) setup.
EDIT: oh yeah, my RAID0-SSD setup also fails with win7.
This comment was edited on Mar 4, 2010, 16:14.