Joystiq follows the VGA GotY win for The Elder Scrolls V: Skyrim by asking Bethesda's Todd Howard about plans for DLC and other post-release support. He explains, without offering too much detail:

Howard couldn't yet share plans for DLC, but he says it will be focused on "ways to make the game better, not just have more, because the game is so big. So we're going through ideas right now, and processing everything people are doing in the game, and trying to think of ways that we can improve it." There will be multiple releases (as with Bethesda's past games), but Howard says they "don't have a timetable. They won't be quick, and they'll have a lot of meat on them."