I had/have no problems running Wasteland in DOSBox. The first time I played it, not long after starting the game I went into a cave and my entire team got killed by rats, mother fucking rats. My elite team of Desert Rangers couldn't hit a damn thing. They used up all of their ammo missing nearly every shot with their pistols before I had to switch to knives and crowbars.
I just realized I had it installed. I loaded it up, and I've been playing it for about an hour. Apparently I had already created a team the last time I played it, but never started the game. I think this team is doing a bit better.