In the Deus Ex lore (assuming Eidos doesn't rewrite it, which they probably will), an earthquake hits the west coast of the US in 2030 and is so disastrous that it sends the country close to bankruptcy. The resulting economic and social problems lead to the formation of the Northwest Secessionist Forces.
Then in the late 2030s a virus spreads around the world and kills millions.
So it might be about these things. I expected DXHR to cover the formation of the NSF actually.