Prez wrote on Nov 11, 2012, 19:51: I was afraid "True Vault Hunter" mode wouldn't be doable in singleplayer, but as it turns out my Commando is doing pretty well. Every fight is a serious affair though, and once I reach the level cap I'm afraid not having a level advantage over the last enemies will make it a major slog or even nigh impossible. I haven't tried Assassin or Mechromancer yet; maybe I'll start over as one of them instead. The differences between the Gunzerker and the Commando aren't the most distinct class differences I've ever seen but each did have a somewhat unique feel.
I was able to complete TVH mode solo on my commando without undue difficulty. It was definitely harder than the first playthrough, but still very doable. Also completed the pirate DLC solo in TVH mode. I used the guerilla skill tree to max out the damage on the turret, which never really falls off.