People seem to be pointing the piracy finger at certain countries without any consideration of the wealth of those countries or it's people. In many of the countries having the finger pointed at them many people are living in conditions places like the US would consider destitute. Now if people in the US have problems with paying $50 for a game how do you think $50 looks to someone who has to worry if they have enough for next weeks food.
Even if the true number of piracy was 99% it doesn't change the fact that if there was no piracy sales number wouldn't change much, infact the only places sales number would really rise are in the wealthy countries like the US where people can afford such inflated prices.
Piracy does not mean a lost sale. This is not just some mantra against those that complain against piracy, it's a cold hard fact.