Obviously you can, as someone is. But most of the tactics you're babbling about will be out the window. This will have the tactics lightly, hopefully brain manipulation, and otherwise exist in the world and atmosphere of the game.
It'll probably be a lot of fun, though not a strict Syndicate game. Given that Syndicate Wars wasn't terribly brilliant, I don't see this as a huge deal. We'll get a fun game. Who cares if it has a name you're crying over?