The National Institute on Media and the Family has issued a statement relating to the AO rating given to Manhunt 2, and the subsequent fallout of that decision. In gloating: "Hopefully Take-Two has learned from its Manhunt 2 experience and will undertake preventive measures to ensure its future games, including Grand Theft Auto IV, are appropriate for families and gamers," they seem to be opining that there aren't any adult gamers, so games targeted at adults are inappropriate:

Minneapolis - The National Institute on Media and the Family today released the following statement in response to Take-Two Interactive Software’s decision to “temporarily suspend” distribution of Manhunt 2. This announcement was in response to the Entertainment Software Rating Board (ESRB) issuing an “Adults-Only” rating for the game and Nintendo and Sony’s decisions to deny Manhunt 2 a license for their products.

“Take-Two’s decision to temporarily suspend distribution of Manhunt 2 is a victory for parents and children.

“Because of the their thoughtful decision to give Manhunt 2 its strongest rating, “Adults-Only,” the ESRB has sent a strong message to Take-Two and other game makers that they no longer can push the envelope on gratuitous violence in video games. The ESRB showed real leadership in assigning this rating and further evidence it is making significant progress in keeping extremely violent and graphic materials out of children’s hands.

“Hopefully Take-Two has learned from its Manhunt 2 experience and will undertake preventive measures to ensure its future games, including Grand Theft Auto IV, are appropriate for families and gamers.

“As gaming technology continues to change, we hope to continue to work with the ESRB to ensure that future games have appropriate content and context for children. The uniqueness of Nintendo’s Wii gives game raters a new challenge when it comes to first-player shooter games. We take the ESRB’s decision about Manhunt 2 as a positive step in addressing this new challenge.”